Author

Jun Han

University of VictoriaORCID 0000-0002-9477-8782Unclaimed ORCID profile · follow to get notified of new preprints

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Jun Han1 paper · University of Victoria

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Adam B. Castoreno· 1 shared Alexandria M. DoerfleriD· 1 shared Ayrea E. HurleyiD· 1 shared Christine BeetoniD· 1 shared Christopher J. WalkeyiD· 1 shared Gang BaoiD· 1 shared Gang LiiD· 1 shared Ivan ZlateviD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Adam B. Castoreno

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1 paper

Recent·Most cited

In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene

Marco De Giorgi, So Hyun Park, Adam B. Castoreno, Mingming Cao, Ayrea E. Hurley, Lavanya Saxena, Marcel A. Chuecos, Christopher J. Walkey, Alexandria M. Doerfler, Mia N. Furgurson, M. Cecilia Ljungberg, Kalyani R. Patel, Sarah Hyde, Tyler Chickering, Stephanie Lefebvre, , William R. Lagor

This paper introduces a method to increase the proportion of correctly repaired hepatocytes in the liver through transient gene inhibition and transgene delivery, achieving a 25% increase in targeted cells and five-fold transgene expression.

Science Translational Medicine · Feb 12, 2025Peer-reviewedGenetics