Eva‐Maria Frickel

Proximity biotinylation at the host-Shigella interface reveals UFMylation as an antibacterial pathway.

The paper identifies UFMylation as an antibacterial pathway using proximity biotinylation and mass spectrometry, showing it targets intracellular Shigella and Salmonella.

Golgi-localised Guanylate-binding protein 5 enhances glycolysis in macrophages

This study identifies GBP5's role in enhancing glycolysis and maintaining Golgi integrity in IFNγ-stimulated macrophages.

GBP1 recruitment to actin-rich pedestals induced by extracellular Gram-negative bacteria promotes pyroptosis.

This study shows GBP1 is recruited to actin-rich pedestals formed by extracellular pathogens, promoting pyroptosis and IL-18 release, independent of LPS.

Mimicry embedding for advanced neural network training of 3D biomedical micrographs

This paper introduces a mimicry embedding strategy to enable efficient deep learning for 3D biomedical micrographs by mimicking verified datasets.