Nipun Verma

This paper introduces CAR-T-drug conjugates (CAR-T-D-C) to improve CAR-T therapy for solid tumors by combining chemotherapy with CAR-T cells, enhancing tumor infiltration and immune response.

The paper introduces TCPGdb, a database integrating T cell perturbation screens to identify critical regulators of T cell function and anti-tumor persistence.

The paper identifies paralog pairs that enhance cancer immunotherapy efficacy through computational analysis and experimental validation.

The paper uses CRISPR-Cas9 screens to identify genes affecting stem cell fitness versus pluripotency identity, finding distinct and overlapping roles for chromatin and metabolic regulators.

The paper identifies actin capping proteins as key modulators of therapeutic responses to radiation and immunotherapy through genome-scale CRISPR screens in melanoma cells.