Author

Qing V. Li

Memorial Sloan Kettering Cancer CenterORCID 0000-0002-0087-9700Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:CRISPR screen· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Bess P. RoseniD· 2 shared Danwei HuangfuiD· 2 shared Dapeng YangiD· 2 shared Hyunwoo ChoiD· 2 shared Jielin YaniD· 2 shared M BeeriD· 2 shared Renhe LuoiD· 2 shared Simone SidoliiD· 2 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersDevelopmental Biology

Bess P. RosenORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness

Bess P. Rosen, Qing V. Li, Hyunwoo Cho, Dingyu Liu, Dapeng Yang, Sarah Graff, Jielin Yan, Renhe Luo, Nipun Verma, Jeyaram Ravichandran Damodaran, Hanuman T Kale, Samuel J. Kaplan, M Beer, Simone Sidoli, Danwei Huangfu

The paper uses CRISPR-Cas9 screens to identify genes affecting stem cell fitness versus pluripotency identity, finding distinct and overlapping roles for chromatin and metabolic regulators.

Nature Communications · Oct 17, 2024Peer-reviewedDevelopmental Biology

Dynamic network-guided CRISPRi screen reveals CTCF loop-constrained nonlinear enhancer-gene regulatory activity in cell state transitions

Renhe Luo, Jielin Yan, Jin Woo Oh, Xi Wang, Dustin Shigaki, Wilfred Wong, Hyunwoo Cho, Dylan Murphy, Ronald R. Cutler, Bess P. Rosen, Julián Pulecio, Dapeng Yang, Rachel A. Glenn, Tingxu Chen, Qing V. Li, , M Beer

The paper uses a CRISPRi screen in hESC differentiation to identify enhancers with nonlinear regulatory activity, revealing a CTCF loop-constrained model for improved enhancer prediction.

Nature Genetics · Jul 24, 2023Peer-reviewedGenetics