Pingzhao Hu

Integrative analysis of taste genetics and the dental plaque microbiome in early childhood caries

This study investigates the relationship between taste-related genetic variants and the dental plaque microbiome in early childhood caries, finding associations with Streptococcus mutans and social factors.

Haploinsufficiency of KPNA7 causes otosclerosis, likely due to the release of import inhibition of PTHrP and the reactivation of chondrogenesis in the globuli interossei

This study identifies a KPNA7 mutation causing otosclerosis by disrupting PTHrP nuclear transport and reactivating chondrogenesis in the otic capsule.

Role of socioeconomic factors and interkingdom crosstalk in the dental plaque microbiome in early childhood caries

This study examines the dental plaque microbiome in early childhood caries, finding associations between specific microbes, socioeconomic factors, and host variables.

Exome-wide tandem repeats confer large effects on subcortical volumes in UK Biobank participants

The paper identifies exome-wide tandem repeats associated with subcortical volumes and psychiatric symptoms in UK Biobank participants.

A multi-tiered map of EMT defines major transition points and identifies vulnerabilities

The paper maps EMT transitions through multi-omic profiling, identifies key regulatory factors, and reveals discordance between molecular layers in human mammary epithelial cells.