Lijun Xia

Development and Function of Ovarian Lymphatic Vasculature

This study investigates the development and function of the ovarian lymphatic vasculature in mice, revealing its origin and the role of VEGF-C/VEGFR-3 signaling in preventing fibrosis and ovarian aging.

S1PR1 Regulates Lymphatic Valve Development And Prevents Ileitis-Independent Tertiary Lymphoid Organ Formation

This study shows that S1PR1 regulates lymphatic valve development and prevents tertiary lymphoid organ formation in the terminal ileum, suggesting TLOs as a sign of subclinical inflammation.

PROX1 inhibits PDGF-B expression to prevent myxomatous degeneration of heart valves

This paper shows that PROX1 inhibits PDGF-B expression in heart valves to prevent myxomatous degeneration, and PDGF-B inhibition ameliorates valve defects in mice.