Monika Priyadarshini

Evolution of mechanical chromatin insulators from selfish genetic elements

The paper shows that DNA sequence-encoded mechanical properties, not just proteins, can create chromatin insulation by transforming Helitron transposons into barrier elements in C. elegans.

An image-based CRISPR screen reveals splicing-mediated control of HP1α condensates

The paper uses an image-based CRISPR screen to show splicing regulates HP1α condensates through RNA-chromatin interactions, affecting heterochromatin organization and stress response genes.

rde-3 reduces piRNA-mediated silencing and abolishes inherited silencing in C. elegans.

The paper demonstrates that rde-3 mutation reduces acute piRNA-mediated silencing and abolishes inherited silencing in C. elegans.

Target-dependent siRNA suppression distinguishes self from non-self endogenous siRNAs in C. elegans germline

The paper shows that siRNA suppression in C. elegans germline depends on target genes, distinguishing self from non-self siRNAs.