Christian Frøkjær‐Jensen

The paper shows that DNA sequence-encoded mechanical properties, not just proteins, can create chromatin insulation by transforming Helitron transposons into barrier elements in C. elegans.

This study shows that HP1 dimerization drives H3K9me chromatin condensation and segregation, while LLPS stabilizes foci, and reveals a decoupling between heterochromatin and transcriptional regulation.

The paper investigates intraspecific variation in the duration of epigenetic inheritance in C. elegans, finding that DNA sequence polymorphisms affect silencing memory across generations.

The paper shows MORC-1 overexpression in csr-1 mutants drives gene downregulation by altering chromatin states, revealing its role in CSR-1-mediated gene licensing.

This study induces in vivo reprogramming in C. elegans and finds it leads to heterogeneous effects on lifespan depending on developmental stage.

The paper demonstrates that rde-3 mutation reduces acute piRNA-mediated silencing and abolishes inherited silencing in C. elegans.

The paper introduces MosTI, a method for targeted transgene insertion in C. elegans using CRISPR/Cas9, enabling efficient single-copy and extrachromosomal array integration.

The paper shows that siRNA suppression in C. elegans germline depends on target genes, distinguishing self from non-self siRNAs.

The paper adapts the SapTrap method to efficiently assemble MosSCI targeting vectors in C. elegans containing promoters, 3UTR, and gene fragments.