Author

Michael P. Tobin

University of PennsylvaniaORCID 0000-0002-9607-2062Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Dennis E. DischeriD· 2 shared Aleksa MilosavljeviciD· 1 shared Alişya A. AnlaşiD· 1 shared Andrew TsourkasiD· 1 shared Anit ShahiD· 1 shared Aparajeeta MajumderiD· 1 shared Breana ChanneriD· 1 shared Carolann L. EspyiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioengineering

Dennis E. DischerORCID

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2 papers

Recent·Most cited

BioengineeringNature NanotechnologyPeer-reviewedAug 11, 2025

Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape without Side Effects

Serena Omo‐Lamai, Yufei Wang, Manthan N. Patel…·Jacob Samuel Brenner

This paper identifies that lipid nanoparticle-induced inflammation arises from endosomal membrane damage and proposes strategies to mitigate it through galectin inhibition or ESCRT-recruiting lipids.

182 citationstop 1%

humanexperimental assay

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BioengineeringProceedings of the National Academy of SciencesPeer-reviewedJul 1, 2025

Clustered macrophages cooperate to eliminate tumors via coordinated intrudopodia

Lawrence J. Dooling, Alişya A. Anlaş, Michael P. Tobin…·Dennis E. Discher

This study shows that macrophage clusters enhance tumor phagocytosis through coordinated intrudopodia extending between cancer cells.

14 citationstop 4%

experimental assayhost-pathogen & immune response

𝕏 PostBluesky