Author

Karl Toischer

Multiscale BioimagingORCID 0000-0002-9644-3716Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

André FischeriD· 2 shared Farahnaz SananbenesiiD· 2 shared M. Sadman SakibiD· 2 shared Ahmed WagdiiD· 1 shared Andreas Unger· 1 shared Anke ZiesenißiD· 1 shared Anna‐Lena Schütz· 1 shared Branimir Berečić· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

André FischerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Peroxisome protein import deficiency causes heart failure in mouse and human

Julia Hofhuis, Malte Tiburcy, Yelena Hartmann, Kristina Bersch, Ahmed Wagdi, Óscar Gutiérrez-Gutiérrez, Richard Solano, Leonie Thiele, Maya Walper, Mona Göbel, Wolfgang Hübner, Branimir Berečić, Marilu Casini, Petros Tirilomis, Andreas Unger, , Sven Thoms

This study shows that peroxisome dysfunction in mice and engineered human myocardium leads to heart failure through metabolic impairment and disrupted cellular respiration.

bioRxiv · Oct 13, 2025 · PreprintCell Biology

NeuID, a novel neuron-specific lncRNA, resolved a key epigenetic mechanisms linking gene silencing to Alzheimer's disease

Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Peña, Eren Diniz, Susanne Burckhardt, Anna‐Lena Schütz, Iga Grządzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulović, , André Fischer

The paper identifies NeuID, a novel neuron-specific lncRNA downregulated in Alzheimer's disease, as a key regulator of neuronal identity and a therapeutic target.

bioRxiv · Jun 1, 2025 · PreprintNeuroscience

Epigenetic gene-expression links heart failure to memory impairment

Rezaul Islam, Dawid Lbik, M. Sadman Sakib, Raoul Maximilian Hofmann, Tea Berulava, Martí Jiménez‐Mausbach, Julia Cha, Maria Goldberg, Elerdashvili Vakhtang, Christian Schiffmann, Anke Zieseniß, Dörthe Magdalena Katschinski, Farahnaz Sananbenesi, Karl Toischer, André Fischer

This study shows heart failure causes hippocampal gene-expression changes leading to memory impairment in mice, and suggests a drug to improve cognition in heart failure patients.

EMBO Molecular Medicine · Jan 20, 2021Peer-reviewedNeuroscience