Author

Claudio J. Villanueva

University of California, Los AngelesORCID 0000-0002-9731-7463Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Peter TontonoziD· 2 shared Prashant RajbhandariiD· 2 shared Anne LoftiD· 1 shared Ezekiel Delgado· 1 shared Hironori WakiiD· 1 shared James Akira WohlschlegeliD· 1 shared Jeixin Wang· 1 shared Jeslyn Zhang· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMolecular Biology

Peter TontonozORCID

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3 papers

Recent·Most cited

Mapping the Glycogen Synthase 1 Interactome in Brown Adipocytes

Jeslyn Zhang, Stefánsdóttir Lára, Sicheng Zhang, Vanja Panic, Vijaya Pandey, Ezekiel Delgado, Julian Wang, James Akira Wohlschlegel, Claudio J. Villanueva

The paper identifies the GYS1 interactome in brown adipocytes using proximity labeling, revealing novel interactors and broader functional roles beyond glycogen synthesis.

bioRxiv · Dec 3, 2025 · PreprintBiochemistry

Transcriptional control of adipogenesis by PATZ1

Sanil Patel, Njeri Z. R. Sparman, Shani Sadeh, Jeixin Wang, Julian P. Whitelegge, Susan K. Fried, Hironori Waki, Claudio J. Villanueva, Marcus Michael Seldin, Shinya Sakaguchi, Wilfried Ellmeier, Peter Tontonoz, Prashant Rajbhandari

This study identifies PATZ1 as an adipogenic transcription factor that promotes adipogenesis through DNA binding and protein interactions, and its loss protects against diet-induced obesity.

bioRxiv · May 24, 2022 · PreprintMolecular Biology

Loss of TLE3 Promotes Mitochondrial Program in Beige Adipocytes and Improves Glucose Metabolism

Stephanie E. Pearson, Anne Loft, Prashant Rajbhandari, Judith Simcox, Sang Hoon Lee, Peter Tontonoz, Susanne Mandrup, Claudio J. Villanueva

This study shows that loss of TLE3 enhances mitochondrial function in beige adipocytes, improves glucose metabolism, and prevents weight gain.

bioRxiv · Sep 5, 2018Developmental Biology