Cristina Concetti

This study shows that MCH signaling influences how reward-guided behavior persists or updates when contingencies change, with MCHR1 blockade reducing perseveration and speeding adaptation.

The paper identifies hypothalamic MCH cells as a neural module that tracks and controls exploratory rearing through interactions with locus coeruleus neurons.

This study shows that MCH neuron activity modulates hippocampal synaptic plasticity and learning speed through optogenetic and in vivo experiments.

This study shows that apical progenitors remain multipotent throughout cortical neurogenesis, reverting their temporal identity and generating neurons from earlier developmental stages.