Stephen L. Mayo

This paper develops a gp120-specific CD4 variant (gCD4) that improves thermostability, reduces off-target class II MHC binding, and enhances HIV-1 neutralization compared to existing CD4-Ig biologics.

This study demonstrates a method to generate antigen-presenting vesicles displaying pMHCI using engineered constructs, which selectively stimulate T cells for potential cell-free immunotherapy.

This paper develops a hydrogel-based biosensor for continuous nicotine measurement in human biofluids, achieving detection at sub-100 nM levels with high stability and sensitivity.

This paper demonstrates that CbAgo-mediated DNA cleavage in E. coli is mutagenic and can be used for genetic manipulation.

ProtaBank is a database for storing and sharing protein design and engineering data, offering tools for analysis and benchmarking predictive models.