Magnus A. G. Hoffmann

This paper develops mRNA-based vaccines encoding RBD quartets and shows they match or improve antibody breadth, T-cell responses, and epitope targeting compared to protein-based vaccines.

This study demonstrates a method to generate antigen-presenting vesicles displaying pMHCI using engineered constructs, which selectively stimulate T cells for potential cell-free immunotherapy.

This study evaluates bivalent S-EABR mRNA-LNP boosters in pre-vaccinated mice, showing enhanced neutralizing responses and polyclass RBD antibody diversity against SARS-CoV-2 variants.

The paper analyzes SARS-CoV-2 spike protein dynamics using eVLPs and HDX-MS, showing the D614G mutation and furin cleavage influence conformational states and infectivity.