Valérie Mongrain

Assessing accelerometry as an alternative to electromyography for mouse sleep scoring

This study evaluates the agreement between electromyography (EMG) and accelerometry (Acc) for sleep scoring in mice, finding high overall accuracy but some bias in Wake and NREM classification.

Electrocorticographic and Astrocytic Signatures of Stearoyl-CoA Desaturase Inhibition in the Triple Transgenic Mouse Model of Alzheimer's Disease

This study investigates whether inhibiting stearoyl-CoA desaturase (SCD) restores sleep in 3xTg-AD mice and affects astrocytic function, finding no significant restoration of sleep patterns but partial rescue of astrocytic changes in the hippocampus.

Transcriptome and proteome associated to the sex-dependent effects of Neuroligin-2 absence on wakefulness and sleep features

The paper investigates sex-dependent effects of NLGN2 absence on sleep and wake states, finding distinct transcriptome and proteome changes in male and female mice.

Cortical miR-709 links glutamatergic signaling to NREM sleep EEG slow waves in an activity-dependent manner

This study shows that miR-709 regulates NREM sleep EEG slow waves by linking glutamatergic signaling to neuronal activity through endosomal trafficking.

Fxr1 regulates sleep and synaptic homeostasis

This study shows Fxr1 is downregulated during synaptic scaling and sleep deprivation, linking it to homeostatic plasticity and sleep regulation.

Reassessing the validity of slow-wave dynamics as a proxy for NREM sleep homeostasis

The paper re-evaluates slow-wave dynamics as a proxy for NREM sleep homeostasis, finding distinct delta-wave types with different responses to sleep deprivation and recovery.