Author

Sara Rodríguez‐Acebes

Spanish National Cancer Research CentreORCID 0000-0002-9867-7591Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:Hi-C· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Juan MéndeziD· 2 shared Alejandra Perona· 1 shared Alejandro Fernández-LlorenteiD· 1 shared Alfonso María ValenciaiD· 1 shared Alicia Gómez-MoyaiD· 1 shared David G. PisanoiD· 1 shared Elena Martín‐DonceliD· 1 shared Emilio LeconaiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Juan MéndezORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The activation of ATR during unperturbed DNA replication is restricted by VCP/p97 through the extraction of DNA polymerase α/Primase from chromatin

Sara Rodríguez‐Acebes, Rodrigo Martín-Rufo, Alicia Gómez-Moya, Scott B Churcher, Alejandro Fernández-Llorente, Guillermo de la Vega-Barranco, Alejandra Perona, Pilar Oroz, Elena Martín‐Doncel, Luis Ignacio Toledo, Juan Méndez, Emilio Lecona

This study shows that VCP/p97 restricts ATR activation during unperturbed S phase by removing DNA polymerase α/Primase from chromatin, preventing excessive replication fork activation and genomic instability.

bioRxiv · Jul 25, 2022 · PreprintMolecular Biology

Three-dimensional connectivity and chromatin environment mediate the activation efficiency of mammalian DNA replication origins

Karolina Jodkowska, Véra Pancaldi, Ricardo Almeida, Maria Rigau, Osvaldo Graña‐Castro, José Miguel Fernández-Justel, Sara Rodríguez‐Acebes, Miriam Rubio-Camarillo, Enrique Carrillo de Santa Pau, David G. Pisano, Fátima Al‐Shahrour, Alfonso María Valencia, Marı́a Gómez, Juan Méndez

The paper investigates how 3D chromatin structure and chromatin environment influence DNA replication origin activation efficiency in mouse embryonic stem cells under stress and control conditions.

bioRxiv · May 29, 2019 · PreprintGenomics