Author
Albert Einstein College of MedicineORCID 0000-0001-9520-3449Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Sarah R. Ocañas, Walker Hoolehan, Kevin D. Pham…·Willard M. Freeman
The paper shows that cell identity and regulatory logic are preserved during brain aging, but cell-type-specific changes occur in DNA modifications and gene expression.
Isaac Kraz, Oi Wei Mak, Subray Hegde…·David Shechter
This study identifies the GNMT N-terminal tail and its phosphorylation at S9 as a regulatory mechanism linking folate feedback to SAM homeostasis.
Shouneng Peng, Erming Wang, Minghui Wang…·Zhidong Tu
The paper identifies an AD-like subtype in brain aging across multiple regions, showing overlap with AD gene signatures and regional differences in gene expression.
Shouneng Peng, Lu Zeng, Jean‐Vianney Haure‐Mirande…·Zhidong Tu
The paper identifies transcriptomic changes in normal aging brains that resemble Alzheimer's disease in specific subgroups, suggesting early molecular links between aging and LOAD.