Manuel R. Plan

This study shows that fusing terpene synthases increases metabolic flux by boosting enzyme stability and expression, leading to higher nerolidol production.

This paper demonstrates that synthetic in vivo compartmentalisation of enzymes in yeast significantly increases product titre and modulates product ratios.

This paper engineers methanol assimilation pathways in yeast and identifies a latent methylotrophic metabolism, improving growth and metabolite labeling through genetic modifications.