Author

Francis Castellino

University of Notre DameORCID 0000-0003-0317-9539Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Victoria A. PloplisiD· 2 shared Alyssa Ann La BellaiD· 1 shared Ana Lidia Flores‐MirelesiD· 1 shared Armando M. MarrufoiD· 1 shared Christopher GageriD· 1 shared Deborah L. DonahueiD· 1 shared Elizabeth R. LucasiD· 1 shared Ellsa Wongso· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersPathology

Victoria A. PloplisORCID

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2 papers

Recent·Most cited

PathologybioRxivPreprintSep 6, 2024

Coagulation factor XII contributes to renin activation, heart failure progression, and mortality

Inna P. Gladysheva, Ryan D. Sullivan, Sofiyan Saleem…·Guy L. Reed

The paper identifies coagulation factor XII as a driver of renin activation, contributing to heart failure progression and mortality.

DOI 10.1101/2024.09.06.611753

humanexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintJul 16, 2024

The catheterized bladder environment induces dysregulation of macrophage polarization exacerbating bacterial UTI

Armando M. Marrufo, Jonathan J. Molina, Christopher Gager…·Ana Lidia Flores‐Mireles

This study shows that fibrin accumulation in a catheterized bladder promotes anti-inflammatory macrophage polarization, which impairs antimicrobial responses and allows bacterial persistence in UTIs.

2 citations

mouseproteomics

𝕏 PostBluesky