Author

Deborah L. Donahue

University of Notre DameORCID 0000-0001-8137-0692Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alyssa Ann La BellaiD· 1 shared Ana Lidia Flores‐MirelesiD· 1 shared Armando M. MarrufoiD· 1 shared Christopher GageriD· 1 shared Elizabeth R. LucasiD· 1 shared Ellsa Wongso· 1 shared Felipe Hiram Santiago-TiradoiD· 1 shared Francis CastellinoiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alyssa Ann La BellaORCID

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1 paper

Recent·Most cited

The catheterized bladder environment induces dysregulation of macrophage polarization exacerbating bacterial UTI

Armando M. Marrufo, Jonathan J. Molina, Christopher Gager, Marissa Jeme Andersen, Alyssa Ann La Bella, Elizabeth R. Lucas, Ellsa Wongso, Tamanna Urmi, Kassandra Arias-Parbul, Railyn Webster, Peter V. Stuckey, Kurt N. Kohler, Deborah L. Donahue, Victoria A. Ploplis, Matthew J. Flick, , Ana Lidia Flores‐Mireles

This study shows that fibrin accumulation in a catheterized bladder promotes anti-inflammatory macrophage polarization, which impairs antimicrobial responses and allows bacterial persistence in UTIs.

bioRxiv · Jul 16, 2024 · PreprintImmunology