Author

Robert A. Nichols

University of Hawaiʻi at MānoaORCID 0000-0003-0366-0162Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:differential expression· 1 Assay:electronic health records· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Amanda J. Lee· 1 shared Ben FogelgreniD· 1 shared Brian E. Hew· 1 shared Cedomir TodoroviciD· 1 shared Chantell Balaan· 1 shared Geetika Y. PatwardhaniD· 1 shared Hanna Kumasaka· 1 shared Jesse B. OwensiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperNeuroscience

Amanda J. Lee

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The exocyst is an insulin-sensitive regulator of amyloid precursor protein trafficking and amyloid-beta generation in neurons

Chantell Balaan, Geetika Y. Patwardhan, Rachel K Sachs, Hanna Kumasaka, Swasthita Sadagopan, Shion Aou, Amanda J. Lee, Luke T. Nelson, Brian E. Hew, Jesse B. Owens, Noémi Polgár, Michael A. Ortega, Robert A. Nichols, Ben Fogelgren

The paper shows the exocyst regulates APP trafficking and amyloid-beta generation in neurons, with insulin signaling shifting exocyst activity away from APP to GLUT4.

bioRxiv · Apr 17, 2026 · PreprintNeuroscience

The Neuroprotective Beta Amyloid Hexapeptide Core Reverses Deficits in Synaptic Plasticity in the 5xFAD APP/PS1 Mouse Model

Kelly H. Forest, Ruth Taketa, Komal Arora, Cedomir Todorovic, Robert A. Nichols

Frontiers in Molecular Neuroscience · Apr 12, 2021Peer-reviewedNeuroscience

Selective co-activation of α7- and α4β2-nicotinic acetylcholine receptors reverses beta-amyloid-induced synaptic dysfunction

Jessica P. Roberts, Sarah A. Stokoe, Matheus Figueiredo Sathler, Robert A. Nichols, Seonil Kim

Journal of Biological Chemistry · Jan 1, 2021Peer-reviewedNeuroscience