Bogdan Iuliu Iorga

The paper identifies three periplasmic enzymes in E. coli that release polysaccharide cargo from the lipid carrier undecaprenyl, revealing a mechanism for bacterial envelope biogenesis and potential antibiotic targets.

The paper identifies a stress-induced membrane insertion mechanism that activates the BepA metalloprotease by displacing its autoinhibitory plug, linking membrane association to protease function.

This paper develops a YOLO-based algorithm to automate LAMP result classification, achieving high accuracy and precision in detecting positive and negative cases.

This study identifies the C-terminal domain (CTD) of BSAP-1 as the receptor-binding region, showing its role in specificity and potential for developing new tools.

This study investigates the structural and functional properties of LppB in Salmonella, showing it modulates outer membrane-peptidoglycan tethering by forming dimers and heterotrimers with Lpp, reducing crosslinking efficiency.

This paper identifies SddA, a periplasmic deacetylase that modulates daughter cell separation in E. coli by modifying denuded peptidoglycan strands, and links its function to amidase activation.

This paper introduces a workflow using AlphaFold and MiniPAE to predict and validate novel Small Linear Motif (SLiM)-mediated protein interactions, demonstrating its effectiveness with RSK kinases.

This study identifies genetic elements critical for pOXA-48 plasmid stability, replication, and conjugative transfer using transposon sequencing.

The paper introduces MICFiller, a Denoising AutoEncoder to impute missing MIC values for Pseudomonas aeruginosa, achieving high accuracy compared to existing methods.