Han K. Remaut

A chaperone-guided donor-strand exchange pathway assembles a Gram-positive pilus

This study identifies a chaperone-guided donor-strand exchange pathway in Enterococcus faecalis that assembles a Gram-positive pilus, revealing a hybrid system combining chaperone-usher and sortase-dependent mechanisms.

Stress-induced Membrane Insertion at the β-Barrel Assembly Machinery Complex Regulates BepA Metalloprotease Activity

The paper identifies a stress-induced membrane insertion mechanism that activates the BepA metalloprotease by displacing its autoinhibitory plug, linking membrane association to protease function.

Yersinia pestis lipoprotein SlyB promotes plague pathogenesis via envelope stress tolerance

This study identifies SlyB as a key lipoprotein in Yersinia pestis that enhances envelope stress tolerance, enabling immune evasion in mammalian hosts but not in flea vectors.

A novel nanobody-based approach for targeting heterogeneous Acinetobacter baumannii isolates and closely related pathogenic Acinetobacter spp.

This paper describes a nanobody-based method for targeting diverse Acinetobacter baumannii isolates and related species, demonstrating its effectiveness in capturing bacteria from complex mixtures.

From fibril to framework: P. abyssi AbpX illuminates a calcium-responsive family of microbial biomatrix proteins that form thermostable hydrogels

This paper investigates AbpX, a microbial biomatrix protein that forms thermostable hydrogels through calcium ion-dependent self-assembly and provides an atomic model of its fibril lattice.

Identification of receptor-binding domains of Bacteroidales antibacterial pore-forming toxins

This study identifies the C-terminal domain (CTD) of BSAP-1 as the receptor-binding region, showing its role in specificity and potential for developing new tools.

Donor Strand Complementation and Calcium Ion Coordination Drive the Chaperone-free Polymerization of Archaeal Cannulae

This study identifies donor strand complementation and calcium ion coordination as key drivers of chaperone-free cannulae polymerization in archaea.

A hierarchical nickel organic framework confers high conductivity over long distances in cable bacteria

This paper identifies the molecular structure of periplasmic fibres in cable bacteria, revealing a nickel-based organic framework that enables long-distance electron transport.

Cryo-EM structure and polar assembly of the PS2 S-layer of Corynebacterium glutamicum

The paper determines the atomic structure of the PS2 S-layer from Corynebacterium glutamicum using cryo-EM and shows its polar assembly mechanism and phylogenetic distribution.

Cryo-EM analysis of the Bacillus thuringiensis extrasporal matrix identifies F-ENA as a widespread family of endospore appendages across the Firmicutes phylum

The paper identifies F-ENA as a widespread family of endospore appendages in Firmicutes using cryo-EM, revealing their structure and role in spore clustering.

The role of endospore appendages in spore-spore contacts in pathogenic bacilli

This study investigates the role of S-ENAs and L-ENAs in spore-spore contacts and their interaction with vegetative cells, revealing their importance in self-aggregation and environmental factors' impact.