Jun Maeda

The paper shows that MRS-measured Glutamate and GABA levels in awake mice correlate with excitatory and inhibitory neural activities during stimulation and in a Dravet syndrome model.

This paper develops [11C]MTP38 as a PET ligand for PDE7 and demonstrates its preclinical success in imaging PDE7 in the brain.

This study tracks tau fibrillogenesis and microglial phagocytosis of neurons in a living tauopathy model, showing that microglia engulf tangle-bearing neurons and that TSPO ligands can reduce this process.

This paper develops a PET-based method using ecDHFR and TMP analogs to image neuronal networks in mammalian brains, enabling visualization of neuronal activity and protein dynamics.