Xiangning Liu

This study identifies a compound that inhibits RhoA activation by stabilizing its GDP state, reducing myocardial remodeling and fibrosis in heart failure models.

This study identifies that the Plasmodium falciparum pantothenate kinase complex has a single active site and that Pf14-3-3I is not essential for its activity but may stabilize the complex.

This study develops pantothenamide-mimics with thiazole rings to overcome degradation by pantetheinase, showing potent antiplasmodial activity and enzyme selectivity.