Author

Luca Boscolo Bielo

Memorial Sloan Kettering Cancer CenterORCID 0000-0003-1026-3923Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

Sarat ChandarlapatyiD· 2 shared Alexandra N. WuestiD· 1 shared Alinur Jaboldinov· 1 shared Allen J. YorkiD· 1 shared Angela N. KoehleriD· 1 shared Anna MalkovaiD· 1 shared Aziz SancariD· 1 shared Benjamin Troness· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Sarat ChandarlapatyORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 2, 2025

A functional map of CDK-drug interactions at single amino acid resolution

Samuel I. Gould, Jonuelle Acosta, Luca Boscolo Bielo…·Francisco J. Sánchez Rivera

The paper maps CDK-drug interactions at single amino acid resolution using genome editing and computational analysis, identifying critical residues and resistance mechanisms.

DOI 10.1101/2025.11.02.685764

humanproteomics

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Cancer BiologybioRxivPreprintJan 18, 2025

Carcinogen-induced DNA adducts amplify APOBEC mutagenesis through nucleotide excision repair

Cameron C. Durfee, Bojana Stefanovska, Rongjie Wu…·Reuben S. Harris

This study shows that carcinogen-induced DNA adducts enhance APOBEC3B-mediated mutagenesis, leading to increased mutation rates in cancer genomes.

4 citations

humanyeast

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