Author

Benjamin Troness

The University of Texas at San Antonio Health Science Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Reuben S. HarrisiD· 3 shared Bojana StefanovskaiD· 2 shared Cameron C. DurfeeiD· 2 shared Christopher D. MullallyiD· 2 shared Harshita B. GuptaiD· 2 shared Joshua ProehliD· 2 shared Michael A. CarpenteriD· 2 shared Nuri A. TemiziD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Reuben S. HarrisORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Endogenous APOBEC3B Promotes CHK1 Inhibitor Sensitivity

Bojana Stefanovska, Benjamin Troness, Christopher D. Mullally, Bárbara de la Peña Avalos, Mahmoud Ibrahim, Yanjun Chen, Elisa Fanunza, Michael A. Carpenter, Reuben S. Harris

This study shows that endogenous APOBEC3B causes DNA damage and replication stress, making cancer cells sensitive to CHK1 inhibitors.

bioRxiv · Aug 5, 2026 · PreprintCancer Biology

Murine models for triple-negative breast cancer with differential responsiveness to immunotherapy

Thomas J. Kalantzakos, Yufan Zhou, Xingyu Liu, Joshua Proehl, Cameron C. Durfee, Ian M. Tamayo, Nuri A. Temiz, Benjamin Troness, Anusha Soni, Harshita B. Gupta, Reuben S. Harris

The paper develops two murine TNBC models with differing immunotherapy responses for studying treatment mechanisms and therapies.

Journal of Clinical and Translational Science · Apr 1, 2026Peer-reviewedCancer Biology

Modeling the role of urokinase plasminogen activator, uPA, and circulating Cancer-Associated Fibroblasts (cCAFS) in breast cancer cell extravasation

Angela K. Spartz, Susan Schmidt, Fazila Mohamed, Benjamin Troness, Carol Ann Lange, Dorraya El‐Ashry

This study shows that circulating cancer-associated fibroblasts (cCAFs) enhance breast cancer cell extravasation by promoting urokinase plasminogen activator (uPA) expression, facilitating metastasis.

bioRxiv · Jun 11, 2025 · PreprintCancer Biology

Carcinogen-induced DNA adducts amplify APOBEC mutagenesis through nucleotide excision repair

Cameron C. Durfee, Bojana Stefanovska, Rongjie Wu, J. Caballero, Mahmoud A. Ibrahim, Michael A. Carpenter, Liping Liu, Shuvro Prokash Nandi, Prokopios P. Argyris, Luca Boscolo Bielo, Eric C. L. Li, Nuri A. Temiz, Yufan Zhou, Erik N. Bergstrom, Christopher D. Mullally, , Reuben S. Harris

This study shows that carcinogen-induced DNA adducts enhance APOBEC3B-mediated mutagenesis, leading to increased mutation rates in cancer genomes.

bioRxiv · Jan 18, 2025 · PreprintCancer Biology