Ivana Barbaric

The paper identifies dynamic changes in rRNA modifications during human embryonic stem cell differentiation using Nanopore sequencing and snoRNA profiling.

The paper shows mitochondrial activity regulates nutrient uptake, affecting BMP4 signaling and spatial organization of germ layers in human gastruloids.

The paper identifies that X chromosome dosage influences aneuploidy development in mouse embryonic stem cells, with XO and XY lines showing higher aneuploidy rates than XX lines.

This study shows that genetic variants in human pluripotent stem cells, specifically gains of chromosome 1q, impair cardiomyocyte differentiation and phenotype through aberrant Wnt activation.

This study identifies hnRNPUL1's role in Integrator-mediated snRNA cleavage and links its mutations to amyotrophic lateral sclerosis.

This study identifies signalling pathways that guide the generation of posterior ventral spinal cord motor neurons from human pluripotent stem cells.

This study shows retinoic acid accelerates the generation of enteric neural progenitors from human pluripotent stem cells, which can form enteric neurons and colonize the ENS in mice.

This study identifies DRP1-mediated mitochondrial dynamics as a regulator of apoptotic response during embryonic differentiation in mouse cells.