Shoichi Tachiyama

This paper models the Shigella T3SS pod complex using AlphaFold, showing two Spa33 proteins bind MxiK and SPOA2-SPOA2 domains, supporting a 1:4:2 stoichiometry and explaining electron density data.

This paper shows that cAMP inputs into a bistable regulatory network drive subpopulations of Pseudomonas aeruginosa cells to prime for T3SS expression.

The paper describes a protein fold switch in a bactericidal nanomachine that enables membrane puncture and bactericidal activity.

This study determines the near-atomic structure of H. pylori sheathed flagella using cryo-EM, revealing how flagellins and glycans contribute to filament stability and motility.

This study uses cryo-electron microscopy to reveal the structure of the Dot/Icm T4SS in Legionella pneumophila, identifying the DotA-IcmX complex as the gatekeeper for effector translocation.

This study investigates OMT formation in F. novicida using cryo-ET and microscopy, revealing envelope modifications and links to type VI secretion and phagosomal membrane changes.

This study builds a near-complete model of the complex flagellar motor in Campylobacter jejuni, revealing its architecture, composition, and evolutionary origins.