Klaus Wunderling

Activation of perivascular thermogenic fat improves aortic stenosis

This study shows that activating perivascular thermogenic fat reduces aortic stenosis in mice and correlates with less severe AS in humans.

Insulin-like peptide secretion is mediated by peroxisome-Golgi interplay

This study shows that peroxisomes interact with the Golgi in Drosophila insulin-producing cells to regulate sphingolipid composition and support insulin-like peptide secretion.

Pseudo-time trajectory of single-cell lipidomics: Suggestion for experimental setup and computational analysis

The paper proposes an experimental setup and computational framework to infer longitudinal single-cell lipid metabolism data from a single destructive measurement.

Creld2 function during unfolded protein response is essential for liver metabolism homeostasis

This study shows that Creld2 is essential for maintaining liver metabolism homeostasis by linking the unfolded protein response (UPR) to metabolic regulation, with sex-specific effects in fatty liver disease.