Alexander Pfeifer

This study shows that activating perivascular thermogenic fat reduces aortic stenosis in mice and correlates with less severe AS in humans.

This study investigates the role of CXCL12 in adipose tissue endothelial cells and finds it dispensable for adipose tissue function under normal and cold conditions, as well as during obesity.

This paper isolates and cultures endothelial cells from brown and white adipose tissue, showing that brown adipose tissue endothelial cells lose their identity in culture and adopt features of white adipose and lymphatic endothelial cells.

This study shows that deleting Adgrf5 in endothelial cells of brown adipose tissue impairs thermogenic capacity during prolonged cold exposure by inducing EndMT and fibro-inflammatory changes.

Shiny-Calorie provides a flexible, open-source tool for analyzing and visualizing indirect calorimetry data, supporting standardized integration and statistical analysis of metabolic phenotyping datasets.

This study identifies miR-196a-5p and miR-342-3p as exomiRs released during exercise that mediate crosstalk between skeletal muscle and thermogenic adipose tissue.

This study investigates the cell type-specific roles of AhR and AhRR in diet-induced obesity and fibrosis, finding that AhRR deficiency protects from metabolic dysfunction and liver damage, while AhR deficiency worsens outcomes.

The paper develops a method to target cardiac scars using genetically modified myofibroblasts guided by magnetic steering, showing improved engraftment and reduced ventricular tachycardia.

This paper introduces Metadatasheet, a metadata standard designed to improve data management by aligning with the data-lifecycle and enabling structured metadata recording in Microsoft Excel.

This study generates transgenic songbirds by efficiently modifying zebra finch primordial germ cells with lentiviral vectors.

The paper investigates glutamate spread in the neuropil using optical reporters and finds that glutamate can activate AMPA and NMDA receptors at distances up to 2 micrometers from the release site.