Raphaël Terreux

This paper reveals that tacrolimus inhibits C. glabrata Cdr1 by stabilizing its inward-facing conformation, blocking ATP hydrolysis and azole transport.

The paper presents cryo-EM structures of the fungal ABC pump Cdr1, revealing its ATP-driven dynamics and drug-binding mechanism.

This study shows that Rhodamine6G binding to BmrA narrows its conformational spectrum, enhancing ATP-dependent transport efficiency.

This study identifies natural inhibitors against Mycobacterium tuberculosis BlaC using molecular docking and simulations, finding Tryptoquivaline K as a stable and promising inhibitor.

This paper identifies leucovorin and dyclonine as pro-oligodendrogenic compounds through pharmacogenomic screening and validates their therapeutic potential in mouse models of myelin pathologies.