Fatemeh Rajaii

Transcriptomic Profiling of Thyroid Eye Disease Orbital Fat Demonstrates Differences in Adipogenicity and IGF-1R Pathway

This study uses single nucleus RNA-Seq to show increased adipogenesis and IGF-1R pathway alterations in TED orbital fat, suggesting linsitinib as a potential therapeutic.

Cell-specific regulation of gene expression using splicing-dependent frameshifting.

This paper introduces SLED, a splicing-based method to control gene expression in specific cell types, demonstrating its utility in targeting neurons, photoreceptors, and cancer cells.

Transcriptomic profiling of human orbital fat and differentiating orbital fibroblasts

The paper uses transcriptomic analysis to compare gene expression in control and TAO patients' orbital fat and differentiating orbital fibroblasts, identifying IGF-1R and Wnt signaling pathway differences.

Cross-species transcriptomic and epigenomic analysis reveals key regulators of injury response and neuronal regeneration in vertebrate retinas.

This study identifies gene regulatory networks controlling proliferative and neurogenic competence in retinal Muller glia.

Comprehensive analysis of retinal development at single cell resolution identifies NFI factors as essential for mitotic exit and specification of late-born cells

The paper uses single-cell RNA sequencing to analyze retinal development stages and identifies NFI factors as regulators of late progenitor cell specification and mitotic exit.