Gianvito Martino

This paper develops a humanized mouse model to study human oligodendrocyte maturation, remyelination, and drug efficacy in spinal cord injury.

The paper identifies distinct microbiome and metabolomic signatures in treatment-naive multiple sclerosis patients compared to healthy controls across multiple biofluids.

TRICS BASIC tested remote ischemic conditioning in experimental stroke, finding improved functional outcomes and reduced infarct volume in rodents.

This study shows that neural precursor cell transplantation improves symptoms of Rett syndrome by activating the Interferon γ pathway.

This study develops a glia-enriched 3D brain model from human iPSCs that mimics MS-related neurodegenerative phenotypes and intercellular communication.

This study identifies a non-neurogenic role of SVZ-eNPCs in regulating striatal GABAergic transmission and decision-making through IGFBPL-1 secretion.

The paper investigates how iPSC-derived neural progeny affect connexin 47 dynamics during demyelination and remyelination, showing their role in panglial network reconstruction.

The paper shows MS-derived oligodendroglia can myelinate axons and form functional connections in a mouse model, suggesting the differentiation block is due to environmental factors, not intrinsic deficits.