Stephanie I. Fraley

This study identifies molecular differences in HR+ breast cancer between Black and White women, linking structural factors like poverty to tumor biology and immune signatures.

The paper introduces the Digital PCR Data Essentials Standard (DDES) to standardize data structure for dPCR, improving interoperability and reproducibility across platforms and applications.

This study develops a cellular phase field model to explain single-cell chiral symmetry breaking under confinement, identifying confinement strength as a key parameter determining rotational behavior.

The paper introduces SuMMIT-SRS, a multiplexed metabolic imaging technique, and demonstrates its application in various cell types to study metabolic rewiring.

This paper shows that matrix degradability affects stress relaxation and cellular mechanics by altering cell spreading and focal adhesions through MMP action.

The paper develops a computational model to predict how collagen matrix microarchitecture affects degradation, showing that enzyme distribution and fibril thickness influence degradability.

The paper introduces a computational model to predict how cellular phenotypes influence mechanotype responses to external signals through intra-cellular signaling networks.

This study develops a network model to investigate how Ca2+ dynamics and signaling crosstalk influence YAP/TAZ activity, revealing frequency-dependent responses and non-monotonic behavior under different stimuli.

This study shows that tuning 3D collagen fibril architecture using PEG affects cancer cell morphology and migration strategies.