Shelton S. Bradrick

The paper characterizes the CAST/EiJ mouse strain as a model for severe COVID-19 by showing it develops high viral burdens, severe lung pathology, and cytokine dysregulation leading to mortality.

This study identifies DDX39B as a regulator of FOXP3 RNA splicing, which influences T regulatory cell fate and immune tolerance, linking it to multiple sclerosis risk.

This study shows RPLP1 and RPLP2 enhance ribosome elongation and protein stability for flaviviral and cellular multi-pass transmembrane proteins by relieving ribosome pausing.

Vorpal constructs interpretable linear models using clustered degenerate K-mers to predict binary phenotypes in RNA viruses, demonstrating its utility in three virus clades.