Linhui Zhai

The paper introduces PTMdecoder, a tool for deconvoluting multiplexed mass spectra to identify and quantify isobaric modification peptidoforms with high sensitivity and accuracy.

This paper introduces a visible-light-controlled cross-linking method for analyzing protein complexes and dynamic interactions in live cells, showing improved accuracy and temporal control.

This study identifies SHP2-driven endothelial activation as a key driver of estradiol-independent endometrial sterile inflammation and shows that targeting SHP2 can alleviate endometrial hyperplasia in mice.