Author

Tithi Mandal

Indian Institute of Science Education and Research KolkataORCID 0000-0003-1672-7880Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

Aurélien RouxiD· 1 shared Bidisha SinhaiD· 1 shared Chinky Shiu Chen LiuiD· 1 shared Deblina Raychaudhuri· 1 shared Dipyaman GangulyiD· 1 shared Fnu AshishiD· 1 shared Juan Manuel GARCIA ARCOSiD· 1 shared Krishnananda ChattopadhyayiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiophysics

Aurélien RouxORCID

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2 papers

Recent·Most cited

BiophysicsMethods in enzymology on CD-ROM/Methods in enzymologyPeer-reviewedJan 1, 2026

✦ In-depth digest

Fluorescence lifetime estimation: a practical approach using Flipper-TR FLIM

Tithi Mandal, Aurélien Roux, Juan Manuel GARCIA ARCOS

Benchmarking fluorescence lifetime estimators for the membrane mechanosensor Flipper-TR across microscopes, laser frequencies, and photon budgets establishes practical guidelines for quantifying relative lipid packing dynamics in live cells.

3 citationstop 1%

mousehuman

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ImmunologybioRxivPreprintJul 31, 2025

Spatio-temporal regulation of ligand trafficking and TLR9 activation involves PIEZO1 mechanosensing in human plasmacytoid dendritic cells

Shrestha Pattanayak, Deblina Raychaudhuri, Purbita Bandopadhyay…·Dipyaman Ganguly

This study identifies PIEZO1 mechanosensing as a key regulator of ligand-specific TLR9 signaling in human pDCs, showing that CpGA induces IFN production via membrane tension and PIEZO1 activation, while CpGB does not.

2 citations

humanproteomics

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