Author

Shrestha Pattanayak

Indian Institute of Chemical Biology

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Immunology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Bidisha SinhaiD· 1 shared Chinky Shiu Chen LiuiD· 1 shared Deblina Raychaudhuri· 1 shared Dipyaman GangulyiD· 1 shared Fnu AshishiD· 1 shared Krishnananda ChattopadhyayiD· 1 shared Nidhi KalidasiD· 1 shared Purbita BandopadhyayiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Bidisha SinhaORCID

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1 paper

Recent·Most cited

Spatio-temporal regulation of ligand trafficking and TLR9 activation involves PIEZO1 mechanosensing in human plasmacytoid dendritic cells

Shrestha Pattanayak, Deblina Raychaudhuri, Purbita Bandopadhyay, Upasana Mukhopadhyay, Tithi Mandal, Chinky Shiu Chen Liu, Nidhi Kalidas, Sumangal Roychowdhury, Krishnananda Chattopadhyay, Fnu Ashish, Bidisha Sinha, Dipyaman Ganguly

This study identifies PIEZO1 mechanosensing as a key regulator of ligand-specific TLR9 signaling in human pDCs, showing that CpGA induces IFN production via membrane tension and PIEZO1 activation, while CpGB does not.

bioRxiv · Jul 31, 2025 · PreprintImmunology