Author

Dipyaman Ganguly

Indian Institute of Chemical BiologyORCID 0000-0002-7786-1795Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Purbita BandopadhyayiD· 2 shared Alain Roger ThierryiD· 1 shared Alice Bibeyran· 1 shared Aliki VasilakouiD· 1 shared Amandine FerrièreiD· 1 shared Aminata Cisse· 1 shared Anaïs RoubertieiD· 1 shared Anne Garreau· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPathology

Purbita BandopadhyayORCID

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2 papers

Recent·Most cited

Extracellular DNASE1L3 dysfunction fuels obesity-driven inflammation and metabolic syndrome

Amandine Ferrière, Anaïs Roubertie, Ekaterina Pisareva, R. Gallo, Purbita Bandopadhyay, Pauline Santa, Anne Garreau, Séverine Loizon, Damien Brisou, Aliki Vasilakou, Aminata Cisse, Maxime Dubois, Blandine Gatta‐Cherifi, Philippe Zizzari, Daniela Cota, , Vanja Sisirak

This study shows that reduced DNASE1L3 activity in obesity leads to increased cfDNA and inflammation, contributing to metabolic syndrome and MASLD, and that restoring DNASE1L3 can mitigate these effects.

bioRxiv · Mar 25, 2026 · PreprintPathology

Spatio-temporal regulation of ligand trafficking and TLR9 activation involves PIEZO1 mechanosensing in human plasmacytoid dendritic cells

Shrestha Pattanayak, Deblina Raychaudhuri, Purbita Bandopadhyay, Upasana Mukhopadhyay, Tithi Mandal, Chinky Shiu Chen Liu, Nidhi Kalidas, Sumangal Roychowdhury, Krishnananda Chattopadhyay, Fnu Ashish, Bidisha Sinha, Dipyaman Ganguly

This study identifies PIEZO1 mechanosensing as a key regulator of ligand-specific TLR9 signaling in human pDCs, showing that CpGA induces IFN production via membrane tension and PIEZO1 activation, while CpGB does not.

bioRxiv · Jul 31, 2025 · PreprintImmunology