Marina F. Caskey

This study shows that sequential vaccination can mature VRC01-class B cells into antibodies that neutralize a broad range of HIV-1 viruses.

This study examines HIV escape from two bNAbs in vivo, identifying recurrent mutations and genetic background dependencies in viral resistance.

The paper identifies early immune responses preceding HIV rebound and links them to viral control outcomes in individuals discontinuing antiretroviral treatment.

This study characterizes HIV reservoir clones and shows they can be culled by sustained CTL pressure, with some displaying intrinsic resistance linked to low oxidative stress.

The paper examines HIV-1 expression in CD4+ T cell clones with latent proviruses, finding heterogeneous expression and limited response to latency reversing agents.

This study examines transcription of HIV-1 at sites of intact latent provirus integration in T cells, finding that latent proviral promoters are significantly less active than in productively infected cells and have minimal impact on neighboring gene expression.

The paper detects and characterizes the SARS-CoV-2 lineage B.1.526 in New York, showing its rapid growth and potential impact on neutralization.