Shayne N. Hassler

This study identifies VLK as an extracellular kinase that mediates EphB2 phosphorylation and pain responses by regulating synaptic protein interactions.

The paper develops a PAR3 agonist and shows it induces mechanical hypersensitivity in mice, suggesting PAR3's role in nociception and plasticity.

This study identifies a specific subset of sensory neurons expressing PAR2 that mediate mechanical and affective pain behaviors, clarifying the cellular basis of PAR2-evoked pain.