Protease-Activated Receptor 2 (PAR2) expressed in sensory neurons contributes to signs of pain and neuropathy in paclitaxel treated mice
Moeno Kume, Ayesha Ahmad, Kathryn DeFea, Josef Vágner, Gregory O. Dussor, Scott A. Boitano, Theodore John Price
This study shows that PAR2 in sensory neurons contributes to paclitaxel-induced pain and neuropathy in mice, and that targeting PAR2 can alleviate these symptoms.
Journal of Pain · Jun 12, 2023Peer-reviewedNeuroscience