Kerui Huang

This study maps spatial metabolic activity in adult fruit flies using isotope tracing and mass-spectrometry imaging, revealing compartmentalized nutrient use across tissues.

FlyAnatoView projects Drosophila scRNA-seq data onto anatomical diagrams to restore spatial context and enable exploration of gene expression patterns across tissues.

The paper identifies genetic interactions of the phosphatidylinositol phosphate signaling pathway in Drosophila spermatogenesis through a sensitized genetic screen.

The paper shows that peroxisomal protein import in Drosophila cortex glia is circadian and affects sleep and lipid metabolism, with Pex5 playing a key role.

The paper shows that lipid metabolism in Drosophila hepatocyte-like cells supports intestinal tumor growth through the TORC1-Hnf4 pathway, with potential therapeutic implications for cancer-associated metabolic dysfunction.

The paper constructs a structure-guided kinase-transcription factor interactome atlas using AlphaFold-Multimer predictions, revealing docking motifs and allosteric hotspots that regulate kinase activity and lipid metabolism.

TransGeneSelector uses a Transformer-based classifier to identify key genes in small plant transcriptomic datasets, outperforming traditional methods in classification and gene discovery.

This study shows that peroxisome import stress reduces ribosome biogenesis and activates the integrative stress response through eIF2α phosphorylation in both Drosophila and human cells.

This study uses RiboTag sequencing to analyze the translatome of Drosophila oenocytes under aging and oxidative stress, identifying shared molecular mechanisms with mammalian liver aging.

This study shows activin signaling negatively regulates cardiac autophagy and health during aging in Drosophila, with mTORC2 playing a key role.