Martin Girard

This paper introduces a multi-chain Hamiltonian replica exchange framework to improve sampling of protein conformations, demonstrating its effectiveness in analyzing transient helices and order-disorder transitions in the IM30 protein.

This study shows phosphorylation of TDP-43's low-complexity domain shifts its self-assembly from macrophase separation to micellization, potentially protecting against pathological aggregation.

This study identifies the structured hairpin region of IM30 as the driver of stress-induced condensate formation in cyanobacteria, linking membrane stress, pH changes, and phase separation.

This paper establishes a framework to understand the behavior of Sturmian polymers, showing molecular grammar arises near the theta transition and determines chain compression/expansion in polymer melts.

This study examines the conformational changes of Nup98-HOXA9's FG domain across different assembly states, revealing micelle-like structures and dynamic transitions during condensate formation.

This study develops a surrogate model for disordered proteins, showing that sequence-dependent radius of gyration is linked to microphase propensity, outperforming existing methods in the crossover region.