Liu H

SP2 impedes the pluripotent-to-totipotent state transition in an RA-dependent manner

This study identifies SP2 as a barrier to the pluripotency-to-totipotency transition in mouse embryonic stem cells, showing its role in promoting alternative developmental programs.

CWF19L2 couples pre-mRNA alternative splicing with the maternal-to-zygotic transition to safeguard female fertility

This study identifies CWF19L2 as a critical regulator of pre-mRNA alternative splicing during the maternal-to-zygotic transition, showing its necessity for female fertility.

Ciz1 safeguards Drosophila wing development by suppressing oxidative stress

This study identifies Drosophila Ciz1 as a factor that prevents oxidative stress and maintains epithelial homeostasis during wing development.

Dual histone methylation reader ZCWPW2 links histone methylation to initiation of meiotic recombination

This study identifies ZCWPW2 as a dual histone methylation reader that links H3K4me3 and H3K36me3 to meiotic DSB formation by interacting with key recombination proteins.