Author
Mayo ClinicORCID 0000-0003-4360-7892Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
John Michael Replogle, Jordan D. Marks, Martin G. Fernandez…·Michael Emmerson Ward
The paper identifies TMEM106B fibril accumulation as a shared mechanism in neurodegeneration linked to genetic variants in TMEM106B and GRN.
Udit Sheth, Rebecca Harrison, Kyle L. Ferber…·Tania F. Gendron
This study compares five NfL immunoassays in plasma and CSF, finding four with excellent performance and noting assay-specific biases and correlations.
Marika Mearelli, Insa Hirschberg, Christin Weissleder…·Michela Deleidi
This study investigates how C9orf72 repeat expansion affects metabolism in human iPSC-derived microglia and its impact on glial-neuronal interactions in ALS.
Suzhou Yang, Denethi Wijegunawardana, Udit Sheth…·Junjie U. Guo
The paper shows that C9ORF72 repeat expansions cause aberrant splicing, leading to exonization and altered RNA processing in ALS/FTD.
Manling Xie, Yong Liu, Shunyi Zhao…·Long‐Jun Wu
This study identifies a novel interaction between TREM2 and TDP-43, showing TREM2 mediates microglial neuroprotection against TDP-43-related neurodegeneration.