Wojciech Pasławski

This study shows that gut-to-brain propagation of alpha-synuclein fibrils induces REM sleep behavior disorder and other non-motor and motor Parkinson's disease phenotypes.

The paper shows that synaptotoxic forms of amyloid-beta and alpha-synuclein act through the same Wnt/PCP pathway to cause dendritic spine loss in neurodegenerative diseases.

This study improves human embryonic stem cell differentiation into midbrain dopaminergic neurons using specific factors and reveals developmental dynamics and high-quality cell types through single-cell RNA-sequencing.

This study shows that PRC2-mediated repression is essential for maintaining identity and function of dopaminergic and serotonergic neurons, with loss leading to behavioral deficits.