Briana R. De Miranda

This study identifies TCE metabolites in mice following inhalation exposure and finds DCA, TCA, and TCEOH-gluc as the most prevalent metabolites, with novel pathway perturbations observed.

This study shows that inhibiting LRRK2 kinase activity reduces ROS and protects against mitochondrial toxicity from environmental toxicants in both in vitro and in vivo models of Parkinson's disease.

This study identifies VGLUT-mediated mechanisms protecting DA neurons from PD-related degeneration, revealing sex-specific effects and transcriptional regulators.

This study shows that low-dose inhalation of trichloroethylene causes dopaminergic neurodegeneration in rodents, mimicking Parkinson's disease pathology.

The paper identifies VGLUT expression as a sex-dependent mediator of age-related dopamine neuron vulnerability in Parkinson's disease.

The paper shows that overexpressing TOM20 in rat midbrain neurons prevents α-synuclein-induced dopaminergic neurodegeneration by restoring mitochondrial protein import.