Daniel L. Aldridge

This study shows that misoprostol reduces C. difficile infection severity by decreasing neutrophil infiltration and G-CSF levels, highlighting innate immune modulation as a therapeutic strategy.

This study shows that IL-27 limits HSPC differentiation during infection and prevents stem cell exhaustion by reducing monocyte production and maintaining HSPC function.

This study shows immune pressure targets Toxoplasma gondii bradyzoites, which mitigate tissue damage and promote host-parasite survival.

This study shows that IL-27, induced by mRNA-LNP vaccines, enhances CD8+ T cell responses through type I IFN signaling, improving vaccine efficacy against pathogens and tumors.